Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical validation of MyCog Mobile: development of a parsimonious and clinically interpretable prediction model for mild cognitive impairment.

JAMIA open·2026
Same author

Dementia Care Research and Psychosocial Factors.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Clinical Manifestations.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Technology and Dementia Preconference.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Clinical validation and machine learning optimization of MyCog: A self-administered cognitive screener for primary care settings.

Alzheimer's & dementia (Amsterdam, Netherlands)·2025
Same author

A comparison of high performance on remote vs. in-person self- administered neuropsychological measures: the Mobile Toolbox and MyCog Mobile.

Journal of clinical and experimental neuropsychology·2025

Related Experiment Video

Updated: Jun 2, 2026

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

Neuro-QOL and the NIH Toolbox: implications for epilepsy.

Cindy J Nowinski1, David Victorson, Jose E Cavazos

  • 1Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine 710 N. Lake Shore Drive, 7th Floor, Chicago, IL 60611, USA.

Therapy (London, England : 2004)
|May 10, 2011
PubMed
Summary

New assessment tools are being developed to better measure the impact of neurological disorders, including epilepsy. These instruments aim to improve the study and treatment of conditions affecting quality of life and neurological function.

More Related Videos

Lipidomics and Transcriptomics in Neurological Diseases
09:58

Lipidomics and Transcriptomics in Neurological Diseases

Published on: March 18, 2022

Related Experiment Videos

Last Updated: Jun 2, 2026

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

Lipidomics and Transcriptomics in Neurological Diseases
09:58

Lipidomics and Transcriptomics in Neurological Diseases

Published on: March 18, 2022

Area of Science:

  • Neurology
  • Health Outcomes Research
  • Psychometrics

Background:

  • Neurological disorders significantly impact patient lives beyond routine clinical assessments.
  • Existing measurement tools for neurological disorder impact are often insufficient, lacking brevity, psychometric soundness, or general acceptance.
  • There is a critical need for validated instruments to assess the multifaceted effects of neurological conditions.

Purpose of the Study:

  • To introduce two NIH-funded initiatives developing novel assessment tools for neurological disorders.
  • To highlight the development of brief, psychometrically sound instruments for measuring health-related quality of life and neurological/behavioral function.
  • To underscore the potential utility of these tools in epilepsy research and treatment, as well as other neurological conditions.

Main Methods:

  • Development of the Neuro-Quality of Life (Neuro-QOL) measures for common neurological disorders.
  • Assembly of the NIH Toolbox for the Assessment of Neurological and Behavioral Function, covering ages 3-85.
  • Creation of assessment tools in both English and Spanish to enhance accessibility and applicability.

Main Results:

  • Neuro-QOL offers a suite of health-related quality of life measures for individuals with prevalent neurological disorders.
  • The NIH Toolbox provides comprehensive measures of cognitive, emotional, motor, and sensory function across a wide age range.
  • Both initiatives are creating validated instruments to address the limitations of current assessment methods.

Conclusions:

  • The developed assessment tools, Neuro-QOL and the NIH Toolbox, are expected to significantly benefit the study and treatment of epilepsy and other neurological conditions.
  • These initiatives provide much-needed, reliable instruments for evaluating the complex impact of neurological disorders on patients' lives.
  • The availability of these tools in multiple languages and across age groups will broaden their research and clinical application.