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Nonrandom secondary chromosome-aberrations in synovial sarcomas with t(x-18)

N Mandahl1, J Limon, F Mertens

  • 1UNIV LUND HOSP,DEPT CLIN PATHOL,S-22185 LUND,SWEDEN. UNIV LUND HOSP,DEPT ORTHOPED SURG,S-22185 LUND,SWEDEN. MED UNIV GDANSK,DEPT BIOL & GENET,GDANSK,POLAND. ST MARYS HOSP,DEPT PATHOL,NEWTON LONGHORNE,PA. KAROLINSKA HOSP,DEPT ORTHOPED,TUMOR SERV,STOCKHOLM,SWEDEN. MED UNIV LODZ,DEPT ONCOL,LODZ,POLAND. CTR ONCOL,KRAKOW,POLAND.

International Journal of Oncology
|May 10, 2011
PubMed
Summary

Synovial sarcoma consistently shows the t(X;18) chromosomal aberration. Additional genetic changes, common in tumors, recurrences, and metastases, may influence disease progression.

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