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Published on: June 21, 2024
Caliceal diverticulum in pediatric patients: the spectrum of imaging findings
Boaz Karmazyn1, Martin Kaefer, S Gregory Jennings
1Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN 46202, USA. bkarmazy@iupui.edu
Insights
Pediatric caliceal diverticulum (CD) often presents with symptoms like infection and stones. Delayed post-contrast CT is highly sensitive for diagnosing CD, which can grow over time.
Area of Science:
- Pediatric Radiology
- Uroradiology
- Pediatric Urology
Background:
- Caliceal diverticulum (CD) is an uncommon pediatric renal anomaly.
- Unlike adults, most pediatric CD cases are symptomatic, often presenting with urinary tract infections or stone formation.
- Accurate diagnosis of pediatric CD is crucial for effective management and preventing complications.
Purpose of the Study:
- To identify and characterize imaging findings of pediatric caliceal diverticulum (CD) at initial diagnosis.
- To evaluate the imaging features of pediatric CD during follow-up examinations.
- To assess the diagnostic accuracy of imaging modalities for pediatric CD.
Main Methods:
- Retrospective review of pediatric patients diagnosed with CD between 2003 and 2010.
- Analysis of presenting symptoms, associated conditions, complications, and management strategies.
- Detailed review of all radiological examinations, including delayed post-contrast CT scans.
Main Results:
- Twenty-four pediatric patients with CD were identified, with ages ranging from 2.6 to 18.5 years.
- Urinary tract infection was the most frequent presentation (n=8).
- Delayed post-contrast CT demonstrated high sensitivity (79%) for CD diagnosis, with only one false-negative case. Most CDs were solitary (n=20), and some grew over time (5/9). Stone formation occurred in 7 patients, and 15 patients required surgical intervention.
Conclusions:
- Pediatric caliceal diverticulum is often solitary, can increase in size, and may be misdiagnosed as other cystic renal lesions.
- Delayed post-contrast CT is a highly sensitive and reliable imaging technique for diagnosing pediatric CD.
- Early and accurate diagnosis of pediatric CD is essential for appropriate management and improved patient outcomes.
Background:
Caliceal diverticulum (CD) is uncommon in children. As compared to adults, most children with CD are symptomatic. Common complications include stone formation and infection. Correct diagnosis of CD is important for guiding management.
Objective:
To identify imaging findings at diagnosis and follow-up in pediatric patients with CD.
Materials And Methods:
We identified all patients from 2003 to 2010 with a diagnosis of CD. We reviewed presenting symptoms, underlying diseases, complications, management, and all pertinent radiological examinations.
Results:
Twenty-four patients (2.6 to 18.5 years old, 11 females) had CD. Urinary tract infection was the most common (n = 8) presentation. Diagnosis of CD was based on delayed post-contrast CT in 79% of patients with only one false-negative CT. Most patients (n = 20) had a single CD; others had either 2 CDs (n = 2) or multiple CDs (n = 2). CD diameter ranged from 1.0 to 18.3 cm and grew in five of nine patients who had follow-up studies. Seven patients developed stone in the CD. Fifteen patients (63%) underwent a surgical procedure.
Conclusions:
CD is commonly solitary, often grows with time and may mimic other diagnoses, including simple cyst, complex cyst and polycystic kidney disease. Delayed postcontrast CT is highly sensitive in diagnosing CD.
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