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How deficient are vitamin D deficient critically ill patients?
1Department of Diabetes and Endocrinology, Princess Alexandra Hospital, School of Medicine, University of Queensland, 199 Ipswich Road, Woolloongabba, Brisbane, Queensland, Australia 4102. p.lee@garvan.org.au
Abstract:
Vitamin D deficiency is highly prevalent among critically ill patients and may be associated with adverse outcomes. Failure of conventional vitamin D supplementation in correcting deficiency has called for studies to evaluate the efficacy and safety of a high-dose regime in critically ill patients. High-dose vitamin D supplementation that corrects a deficient state effectively and safely allows for intervention studies to be undertaken to determine the impact of vitamin D on morbidity and mortality in critically ill patients.
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