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SCA3 presenting as an isolated axonal polyneuropathy
Tracey D Graves1, Roberto J Guiloff
1Neuromuscular Unit, West London Neurosciences Centre, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road, London, United Kingdom.
Objectives:
To highlight an unexpected clinical presentation and to review the associated polyneuropathy phenotypes of SCA3.
Design:
Clinical follow-up.
Setting:
Neurological referral center.
Patient:
Middle-aged man with no family history for SCA3.
Results:
Presentation with an isolated axonal, distal, symmetric, sensorimotor polyneuropathy for 6 years before developing a cerebellar syndrome prompting genetic testing for SCA3.
Conclusion:
SCA3 can present with an isolated axonal, distal, symmetric, sensorimotor polyneuropathy.
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