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Published on: November 20, 2015
Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study
Dymph J Mesker1, Mariëlle M F Poels, M Arfan Ikram
1Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Objective:
To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds.
Design:
Population-based, cross-sectional analysis.
Setting:
The Rotterdam Scan Study.
Participants:
A total of 198 persons (age range, 61-95 years) with lobar microbleeds.
Main Outcome Measures:
Distribution of microbleeds over different lobes.
Results:
We found that lobar cerebral microbleeds occurred significantly more often in the temporal lobe, a region known to be more affected in cerebral amyloid angiopathy.
Conclusion:
This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.
