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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
[Rosai -Dorfman disease: a two cases report]
Hadhami Ben Turkia1, Manal Ben Romdhane, Hatem Azzouz
1Hopital La Rabta, Tunis, Tunisie.
La Tunisie Medicale
|May 11, 2011
Summary
Rosai-Dorfman disease (RDD) is a rare benign lymphoproliferative disorder. This report details two pediatric cases, highlighting varied presentations and management challenges for this uncommon condition.
Area of Science:
- Pediatric Hematology Oncology
- Dermatopathology
- Head and Neck Pathology
Background:
- Rosai-Dorfman disease (RDD) is a rare, benign lymphoproliferative disorder.
- Characterized by cervical lymphadenopathy, RDD can cause airway compression and cosmetic issues.
- Extranodal RDD presentations are also documented.
Observation:
- Two pediatric cases of RDD are presented.
- Case 1: Prolonged nodal RDD with apparent natural remission, possibly influenced by sulfamethoxazole-trimethoprim.
- Case 2: Extranodal RDD involving soft tissue, paranasal sinus, and nasal cavity, responsive to corticosteroids.
Findings:
- RDD typically presents as a benign condition.
- Varied clinical manifestations include nodal and extranodal involvement.
- Treatment response can differ significantly between presentations.
Implications:
- Understanding RDD's diverse presentations is crucial for diagnosis.
- Effective therapeutic strategies for RDD remain an area of investigation.
- The risk of recurrence in RDD necessitates long-term monitoring.
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