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Related Experiment Videos

Malaria at delivery in Abidjan.

M C Reinhardt, P Ambroise-Thomas, R Cavallo-Serra

    Helvetica Paediatrica Acta. Supplementum
    |December 1, 1978
    PubMed
    Summary

    Malaria during pregnancy significantly impacts infant health, causing low birthweights and premature births. This study highlights the prevalence of malaria in expectant mothers and newborns in a holoendemic region.

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    Area of Science:

    • Obstetrics and Gynecology
    • Infectious Diseases
    • Pediatrics

    Background:

    • Malaria poses a significant threat to maternal and infant health, particularly in holoendemic regions.
    • Understanding the prevalence and impact of malaria during pregnancy is crucial for effective public health interventions.

    Purpose of the Study:

    • To determine the prevalence of malarial parasitaemia in mothers and newborns during delivery.
    • To investigate the relationship between malaria, parity, birthweight, and gestational age.
    • To assess the incidence of intrauterine infections in newborns.

    Main Methods:

    • A study was conducted on 198 consecutive deliveries in a malaria-holoendemic region.
    • Mothers' blood and umbilical cord blood were analyzed for malarial parasitaemia.
    • Infant birthweights and gestational ages were recorded.
    • Newborn IgM concentrations were measured to detect intrauterine infections.

    Main Results:

    • 39.4% of mothers exhibited malarial parasitaemia, with 55% of infected mothers having malaria in cord blood.
    • Malaria incidence decreased with increasing parity, suggesting an age-related protective effect.
    • Malaria was found to be a contributing factor to low birthweight, preterm birth, and small-for-date infants.
    • A correlation was observed between maternal nutritional status and malarial infection.
    • 2.5% of newborns showed signs of intrauterine infection based on cord blood IgM levels.

    Conclusions:

    • Maternal malaria is prevalent in holoendemic areas and significantly affects pregnancy outcomes.
    • Malaria contributes to adverse birth outcomes, including low birthweight and preterm delivery.
    • Further research into the interplay of malaria, nutrition, and parity is warranted to improve maternal and child health.

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