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Related Experiment Video

Updated: Jun 2, 2026

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Abnormalities of object visual processing in body dysmorphic disorder.

J D Feusner1, E Hembacher, H Moller

  • 1Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. jfeusner@mednet.ucla.edu

Psychological Medicine
|May 12, 2011
PubMed
Summary
This summary is machine-generated.

Individuals with body dysmorphic disorder (BDD) exhibit altered brain activity when viewing objects, showing reduced processing of low-detail images and different engagement with high-detail stimuli. This suggests broader visual processing differences beyond appearance-related concerns.

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Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Psychiatry

Background:

  • Body dysmorphic disorder (BDD) is linked to perceptual distortions, particularly in visual processing of faces.
  • Previous research indicates imbalances in detailed versus holistic visual processing in BDD.
  • Neural correlates of processing non-symptom-related stimuli in BDD remain unexplored.

Purpose of the Study:

  • To investigate if individuals with BDD display abnormal brain activation patterns when viewing non-face/non-body object stimuli.
  • To examine neural correlates of processing objects with varying spatial frequencies in BDD.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was used to scan 14 participants with BDD and 14 healthy controls.
  • Participants matched house images varying in spatial frequency: high detail (HSF) and low detail (LSF).
  • Blood oxygen level-dependent (BOLD) signal changes were analyzed for group differences.

Main Results:

  • The BDD group exhibited reduced activation in visual association areas (parahippocampal gyrus, lingual gyrus, precuneus) for LSF (holistic) images.
  • Increased activation in medial prefrontal regions was observed for HSF (detailed) images in the BDD group.
  • Greater BDD symptom severity correlated with lower activation in dorsal occipital and ventrolateral prefrontal cortex for normal and HSF images.

Conclusions:

  • Individuals with BDD demonstrate aberrant brain activation when processing objects, not solely appearance-related stimuli.
  • Hypoactivity for holistic processing and altered prefrontal engagement for details suggest global-local processing imbalances.
  • These findings may extend beyond appearance concerns, indicating broader visual processing atypicalities in BDD.