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Updated: Jun 2, 2026
12:18
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Peripheral venous catheter-related Staphylococcus aureus bacteremia
T Tony Trinh1, Philip A Chan, Omega Edwards
1Department of Medicine, Rhode Island Hospital, and Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Infection Control and Hospital Epidemiology
|May 12, 2011
Summary
Peripheral venous catheter (PVC)-related Staphylococcus aureus bacteremia is an underrecognized issue. Infections are linked to emergency department or outside insertions, antecubital fossa placement, and prolonged catheter dwell times.
Area of Science:
- Infectious Diseases
- Hospital Epidemiology
- Medical Device Infections
Background:
- Peripheral venous catheters (PVCs) are common in hospitalized patients.
- Catheter-related bloodstream infections (CRBSIs) pose significant risks.
- Staphylococcus aureus bacteremia is a serious complication of invasive devices.
Purpose of the Study:
- To determine the incidence, risk factors, and outcomes of PVC-related Staphylococcus aureus bacteremia.
- To estimate the national burden of these infections.
- To identify specific PVC insertion characteristics associated with S. aureus bacteremia.
Main Methods:
- Retrospective study of adult patients with PVC-related S. aureus bacteremia from July 2005 to March 2008.
- Point-prevalence survey to assess PVC utilization.
- Case-control analysis to identify risk factors for infection.
Main Results:
- An estimated incidence density of 0.07 per 1,000 catheter-days for PVC-related S. aureus bacteremia.
- Risk factors included antecubital fossa placement (OR, 6.5), emergency department insertion (OR, 6.0), and outside hospital placement (P = .005).
- Prolonged catheter dwell time (P < .001) was also a significant risk factor; 42% of cases had complications.
Conclusions:
- PVC-related S. aureus bacteremia is an underrecognized complication.
- Specific insertion sites (emergency department, outside institutions, antecubital fossa) and prolonged dwell times increase infection risk.
- An estimated 10,028 yearly cases in US adult inpatients highlight the need for improved prevention strategies.
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