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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Acute upper airway obstruction
K Sasidaran1, Arun Bansal, Sunit Singhi
1Department of Pediatrics, Advanced Pediatrics Centre, PGIMER, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Insights
Recognizing upper airway obstruction signs like stridor is crucial for prompt diagnosis and treatment in children. Early intervention and targeted therapies based on the cause, such as croup or diphtheria, improve patient outcomes.
Area of Science:
- Pediatrics
- Emergency Medicine
- Otolaryngology
Background:
- Upper airway obstruction (UAO) presents with stridor, suprasternal retractions, and voice changes.
- Common causes in children include infectious etiologies like croup and diphtheria.
- Bacterial tracheitis is increasingly reported as a serious cause of UAO.
Purpose of the Study:
- To outline the evaluation and management of pediatric upper airway obstruction.
- To differentiate common causes of UAO based on clinical presentation.
- To detail specific treatments for various UAO etiologies.
Main Methods:
- Clinical data assessment including onset, fever, stridor character, and secretions.
- Severity assessment of respiratory distress.
- Diagnostic considerations for infectious and non-infectious causes of UAO.
Main Results:
- Croup is the most common cause; diphtheria is life-threatening.
- Bacterial tracheitis is a growing concern.
- Prompt airway management (intubation/tracheostomy) is vital for audible stridor.
Conclusions:
- Effective management of pediatric UAO requires prompt recognition and specific treatment tailored to the underlying cause.
- Timely administration of medications like corticosteroids, epinephrine, antibiotics, and antitoxins is critical.
- Consultation with specialists and transfer to pediatric intensive care unit (PICU) may be necessary for severe cases.
Abstract:
Upper airway obstruction is defined as blockage of any portion of the airway above the thoracic inlet. Stridor, suprasternal retractions, and change of voice are the sentinel signs of upper airway obstruction. Most of the common causes among children presenting to emergency department are of acute infectious etiology. Among these, croup is the commonest while diphteria remains the most serious life-threatening cause. Recent reports indicate that bacterial tracheitis has become increasingly common. In ER evaluation the key clinical data in determining the cause and the site of obstruction are the onset, presence of fever, character of the stridor, retractions, the voice and the ability to handle secretions. After assessment of the severity of respiratory distress and resuscitative or supportive therapy including oxygen and emergent airway, specific treatment is directed at underlying etiology. All patients with audible stridor require early endotracheal intubation/tracheostomy. In croup the mainstay of treatment are cold humidified oxygen, budesonide nebulization ( in mild cases), Dexamethasone 0.6 mg/kg iv or im (in moderate and severe cases), and Adrenaline 5 ml 1:1000 (5 mg) solution as nebulization ( in severe cases). In diphtheria, early tracheostomy, anti-diphtheric serum and injectable penicillin are critical. Bacterial Tracheitis and Retropharyngeal abscess need early administration of injectable Cloxacillin, Amikacin and Clindamycin. ENT consultation should be obtained for early surgical drainage of retropharyngeal abscess. Angioneurotic edema is treated with subcutaneous adrenaline (1:1000, 0.01 ml/kg); hydrocortisone 10 mg/kg IV and antihistamines. Patients with severe obstruction and those with endotracheal tube/ trachesotomy should be transferred to PICU.
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