Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 2, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
09:48

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

[Endometrial carcinoma].

K Engelhard1

  • 1Krankenhaus Martha-Maria, Stadenstr. 58, Nürnberg, Deutschland. k.engelhard@martha-maria.de

Der Radiologe
|May 12, 2011
PubMed
Summary
This summary is machine-generated.

Magnetic resonance imaging (MRI) is the gold standard for staging endometrial cancer, accurately differentiating early from advanced myometrial invasion and assessing lymph node involvement. MRI is crucial for guiding treatment decisions and detecting recurrence.

Related Concept Videos

Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Chances and challenges of increasing digitalization of teaching in the discipline anesthesiology from the perspective of students].

Die Anaesthesiologie·2022
Same author

Non-invasive haemoglobin measurement as an index test to detect pre-operative anaemia in elective surgery patients - a prospective study.

Anaesthesia·2020
Same author

[54-year-old female with sudden onset unbearable headache in the domestic environment : Preparation for the medical specialist examination: Part 19].

Der Anaesthesist·2019
Same author

Guidelines for the Treatment of Head Injury in Adults.

Journal of neurological surgery. Part A, Central European neurosurgery·2017
Same author

Cerebral oxygen saturation and cardiac output during anaesthesia in sitting position for neurosurgical procedures: a prospective observational study.

British journal of anaesthesia·2017
Same author

[Neuroanesthesia].

Der Anaesthesist·2015

Area of Science:

  • Oncology
  • Radiology
  • Medical Imaging

Context:

  • Endometrial cancer staging is critical for determining appropriate treatment strategies.
  • Accurate tumor staging influences surgical procedures and the need for adjuvant therapies like radiotherapy.
  • Magnetic resonance imaging (MRI) has emerged as a primary diagnostic tool in this field.

Purpose:

  • To evaluate the efficacy of MRI in staging endometrial cancer, including myometrial invasion and lymph node metastasis.
  • To compare the diagnostic performance of MRI with other imaging modalities such as vaginal ultrasound and computed tomography.
  • To highlight the role of MRI in treatment planning and detecting cancer recurrence.

Summary:

  • MRI demonstrates high sensitivity (85-95%) in differentiating early (stage IA) from deep (stage IB) myometrial invasion.

Related Experiment Videos

Last Updated: Jun 2, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
09:48

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

  • For cervical invasion, MRI offers 80% sensitivity and 96% specificity.
  • MRI shows a 50% sensitivity and 95% specificity for detecting lymph node metastases, with 90% accuracy.
  • Compared to vaginal ultrasound (73-95%) and computed tomography (61-76%), MRI provides superior staging accuracy.
  • MRI is identified as the most valuable tool for radiotherapy planning and identifying cancer recurrence.

    • Impact:

    • Accurate staging via MRI enables personalized treatment, moving from simple hysterectomy for early stages to extended procedures with radiotherapy for advanced disease.
    • The diagnostic precision of MRI aids in optimizing surgical interventions and adjuvant treatment protocols.
    • MRI's effectiveness in detecting recurrence supports improved patient monitoring and follow-up care.