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Updated: Jun 2, 2026
03:26
Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
Detrusor after-contraction is associated with bladder outlet obstruction.
Sung Yong Cho1, Jun-Seok Yi, Ji Hyun Park
1Department of Urology, Seoul National University College of Medicine, Seoul, Korea.
Neurourology and Urodynamics
|May 12, 2011
Summary
Detrusor after-contraction (DAC) can be distinguished from artifacts using a cough test. The presence of DAC is linked to bladder outlet obstruction (BOO), particularly in older males and those with benign prostatic hyperplasia.
Area of Science:
- Urology
- Physiology
Background:
- Detrusor after-contraction (DAC) is a phenomenon observed during micturition that requires differentiation from artifacts.
- Understanding the clinical significance of DAC is crucial for accurate diagnosis and patient management.
Purpose of the Study:
- To establish methods for differentiating true detrusor after-contractions (DAC) from artifacts.
- To investigate the clinical implications and significance of DAC in patients with voiding dysfunction.
Main Methods:
- Retrospective analysis of 2,309 patients with voiding dysfunction.
- Utilized a cough test to differentiate DAC from artifacts during detrusor pressure monitoring.
- Patients were subcategorized based on postvoid urine volume, electromyographic activity, and pressure changes.
Main Results:
- Detrusor after-contraction (DAC) was identified in 10.6% of patients, with artifacts accounting for 23.3% of these events.
- DAC was more prevalent in males (5.7%) than females (2.4%), increasing with age in males.
- Patients with DAC exhibited higher detrusor pressures and an increased risk of bladder outlet obstruction (BOO), especially those with benign prostatic hyperplasia.
Conclusions:
- A cough test is effective in differentiating detrusor after-contractions (DAC) from artifacts.
- The presence of DAC is significantly correlated with bladder outlet obstruction (BOO).
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