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Constitutive expression of HIV-1 tat protein in human Jurkat T cells using a BK virus vector
A Caputo1, J G Sodroski, W A Haseltine
1Division of Human Retrovirology, Dana-Farber Cancer Institute, Boston, MA 02115.
Abstract:
The production and characterization of Jurkat cell lines that constitutively express functional human immune deficiency virus type 1 (HIV-1) tat protein, using a BK virus plasmid expression vector and HIV-1 tat cDNA, is described. An increased growth rate of these Jurkat-tat cell lines as compared with control cell lines was observed.
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