Neurofibromatous neuropathy
P K Thomas1, R H King, T R Chiang
1Royal Free Hospital School of Medicine, Queen Square, London, UK.
Muscle & Nerve
|February 1, 1990
Abstract:
Three cases of chronic distal sensorimotor neuropathy are described in patients with neurofibromatosis. One had type 2 or central neurofibromatosis with a chromosome 22 deletion; the precise form of the disease was not established in the other two. A striking clinical feature was a diffuse nodular enlargement of the peripheral nerves. Nerve biopsies from all three cases demonstrated the presence of neurofibromatous pathology. Neurofibromatous neuropathy constitutes a rare manifestation of neurofibromatosis, related to diffuse neurofibromatous changes in the peripheral nerves.
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