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Published on: July 9, 2012
Method for phenotypic detection of extended-spectrum beta-lactamases in enterobacter species in the routine clinical
James Cohen Stuart1, Bram Diederen, Nashwan Al Naiemi
1Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands. j.cohenstuart@umcutrecht
Abstract:
In 271 Enterobacter blood culture isolates from 12 hospitals, extended-spectrum beta-lactamase (ESBL) prevalence varied between 0% and 30% per hospital. High prevalence was associated with dissemination, indicating the potential relevance of infection control measures. Screening with cefepime or Vitek 2, followed by a cefepime/cefepime-clavulanate Etest, was an accurate strategy for ESBL detection in Enterobacter isolates (positive predictive value, 100%; negative predictive value, 99%).
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