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Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts

Lisa Fellner1, Kurt A Jellinger, Gregor K Wenning

  • 1Division of Clinical Neurobiology, Department of Neurology, Innsbruck Medical University, Austria.

Acta Neuropathologica
|May 13, 2011
PubMed
Summary

Glial cells, including astrocytes, microglia, and oligodendrocytes, play a critical role in neurodegenerative diseases like Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Understanding glial dysfunction is key to developing new therapies for these α-synucleinopathies.

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