Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Leisure-time physical activity and low back pain in Switzerland: results from the 2022 cross-sectional Swiss Health Survey.

BMC musculoskeletal disorders·2026
Same author

Systematic Review Evaluating the Influence of Veneering Design on the Clinical Outcome of All-Ceramic Implant-Supported 3-4 Units and Full Arch Fixed Dental Prostheses.

Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]·2026
Same author

Diet, lifestyle, and sociodemographic influences on serum concentration of PFASs: Insights from human biomonitoring in Switzerland.

Environment international·2026
Same author

Between-Hospital Variation in Failure to Rescue After Major Surgery.

JAMA network open·2026
Same author

Occupational exposures and skin cancer incidence in six Swiss cantons.

The Science of the total environment·2025
Same author

[HPV self-sampling and cervical cancer screening].

Revue medicale suisse·2025

Related Experiment Video

Updated: Jun 2, 2026

Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy
06:00

Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy

Published on: May 27, 2022

Selenium for preventing cancer.

Gabriele Dennert1, Marcel Zwahlen, Maree Brinkman

  • 1Institut für Transdisziplinäre Gesundheitsforschung, Graefestrasse 16, Berlin, Germany, D-10967.

The Cochrane Database of Systematic Reviews
|May 13, 2011
PubMed
Summary
This summary is machine-generated.

Higher selenium exposure may reduce cancer incidence and mortality, particularly in men. However, selenium supplements have not shown convincing evidence for cancer prevention in humans.

More Related Videos

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module
10:39

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Published on: June 18, 2015

Related Experiment Videos

Last Updated: Jun 2, 2026

Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy
06:00

Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy

Published on: May 27, 2022

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module
10:39

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Published on: June 18, 2015

Area of Science:

  • Nutritional Science
  • Oncology
  • Epidemiology

Background:

  • Selenium is an essential trace element for human health.
  • Previous research suggests a potential protective role of selenium against various cancers.

Purpose of the Study:

  • To review the evidence on the relationship between selenium exposure and cancer risk.
  • To assess the efficacy of selenium supplementation for cancer prevention.

Main Methods:

  • Included prospective observational studies for etiological relationships.
  • Included randomized controlled trials (RCTs) for supplementation efficacy.
  • Conducted random effects meta-analyses for epidemiological data and narrative summaries for RCTs.

Main Results:

  • Higher selenium exposure was associated with reduced cancer incidence (OR 0.69) and mortality (OR 0.55) in observational studies, with a more pronounced effect in men.
  • RCTs found no protective effect of selenium yeast or L-selenomethionine supplementation against specific cancers.
  • Inconsistent results and concerns about potential harm were noted for selenium supplements in some trials.

Conclusions:

  • No definitive causal link between low selenium exposure and increased cancer risk can be established.
  • Evidence for an inverse association between selenium exposure and cancer risk requires careful interpretation due to study limitations.
  • There is currently no convincing evidence that selenium supplements prevent cancer in any population group.