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Updated: Jun 2, 2026

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
Published on: September 20, 2020
Minimally invasive transradial intervention using sheathless standard guiding catheters
Aaron M From1, Malcolm R Bell, Charanjit S Rihal
1Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Objectives:
We evaluated a sheathless transradial technique for interventions using standard five and six French nonhydrophilic guiding catheters.
Background:
Miniaturization of transradial interventions may serve to improve patient comfort and reduce the risk of access-site complications. Guiding catheters carry an outer diameter approximately 2 Fr sizes smaller than their corresponding introducer sheaths.
Methods:
We identified consecutive patients who underwent transradial intervention between August 2010 and December 2010 using 5 or 6 Fr guides with a sheathless technique.
Results:
A total of 11 patients were identified (mean age 70.7 ± 10.9 years; 73% male). Single coronary intervention was performed in 10 patients and renal artery intervention in one. Right radial access and 6 Fr guide catheters were used in the majority (each 73%). Five techniques were used to create an inner dilator as the taper. Four of these inner tapers (standard diagnostic catheters, hydrophilic diagnostic catheters, long sheath dilators and guide extensions) enabled successful sheathless guide insertion in all 10 patients attempted. One technique (a partially inflated angioplasty balloon protruding from the guide) attempted in one patient was unsuccessful. All interventional procedures were successful, there were no radial artery access-site complications and in no case was cross-over to femoral artery access-site required.
Conclusion:
Sheathless transradial intervention using standard 5 and 6 Fr guiding catheters is a safe and effective method for treatment of coronary and peripheral vascular lesions.
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