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[Testing for hepatitis C]
Insights
Hepatitis C virus (HCV) causes approximately 12% of all hepatitis cases in Austria. High prevalence was observed in Austrian drug addicts (80%) and polytransfused patients (44.8%).
Area of Science:
- Virology
- Infectious Diseases
- Hepatology
Context:
- Hepatitis diagnosis at Vienna University over 10 years revealed diverse etiological agents.
- Non-A, non-B hepatitis (NANB) constituted 25.8% of diagnosed cases.
- Hepatitis C virus (HCV) was investigated as a primary cause of NANB.
Purpose:
- To determine the prevalence of hepatitis C virus (HCV) in Austria.
- To identify risk groups associated with HCV infection.
- To analyze the etiological spectrum of hepatitis cases.
Summary:
- Hepatitis C virus (HCV) was detected in 9.6% of acute and 44.9% of chronic non-A, non-B hepatitis cases.
- An estimated 12% of all hepatitis cases in Austria are attributed to HCV.
- High HCV prevalence was noted in drug addicts (80%), polytransfused patients (44.8%), and within a specific dialysis unit (30%).
Impact:
- This study highlights the significant burden of hepatitis C in Austria.
- Identifies key populations at high risk for HCV infection, informing targeted public health interventions.
- Provides crucial epidemiological data for hepatitis C prevention and control strategies in the region.
Abstract:
Over the past 10 years, 12,146 cases of hepatitis were diagnosed in the Virology Department of Vienna University. 30.3% were hepatitis A, 39.2% hepatitis B, 3.0% cytomegalovirus and 1.5% Epstein-Barr virus infections. The remaining 25.8% were diagnosed as non-A, non-B hepatitis (NANB). Therefrom, a sample of 167 sera from acute and 78 from chronic hepatitis NANB were tested for hepatitis C. 9.6% of the acute and 44.9% of the chronic cases were positive. We conclude from these data that about 12% of all hepatitis cases in Austria are caused by the hepatitis C virus. In addition, risk groups for hepatitis C were tested. The highest prevalence (80%) was found in drug addicts. Polytransfused (organ transplanted) patients had antibodies in 44.8% of cases. Of 78 dialysis patients, 7 were positive but nearly all positives came from one single dialysis unit, thus indicating a prevalence of 30% there.
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