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Clinical pharmacokinetics of daptomycin
R D Pryka1, R M Novak, D K Wagner
1Clinical Pharmacokinetics and Infectious Diseases, College of Pharmacy, University of Toledo, OH.
DICP : the Annals of Pharmacotherapy
|March 1, 1990
Summary
This study examined the pharmacokinetics of daptomycin, an antibiotic, in an adult patient. Daptomycin dosing showed consistent pharmacokinetic profiles between the first and fifth doses, similar to healthy volunteers.
Area of Science:
- Pharmacology
- Infectious Diseases
- Clinical Pharmacy
Background:
- Daptomycin is a novel lipopeptide antibiotic.
- Limited pharmacokinetic data exists for adults, primarily in healthy volunteers and renally impaired patients.