Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmaceutical Poisoning: Treatment Strategies01:26

Pharmaceutical Poisoning: Treatment Strategies

Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...
Toxidromes: Clinical Features01:30

Toxidromes: Clinical Features

Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The toxicology and characteristics of fatal new psychoactive stimulant and hallucinogen-related poisonings in Australia, 2000-2025.

Drug and alcohol dependence reports·2026
Same author

Holistic approach to substance-induced psychosis.

Addiction (Abingdon, England)·2026
Same author

Changing characteristics in the 2020s of fatal 'novel' benzodiazepine toxicity cases in Australia.

Drug and alcohol dependence·2026
Same author

Trends in gamma-hydroxybutyrate use, harms and treatment in Australia, 2013 to 2024.

Addiction (Abingdon, England)·2026
Same author

Commentary on Chang et al.: Drugs, disease and death.

Addiction (Abingdon, England)·2025
Same author

Women using menopausal hormone therapy who suicide have multiple risk factors.

Maturitas·2025

Related Experiment Video

Updated: Jun 2, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

Oxycodone poisoning: not just the 'usual suspects'.

Shane Darke

    Addiction (Abingdon, England)
    |May 14, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Oxycodone dependence is a significant global health issue. Public health efforts have overlooked individuals dependent on oxycodone without prior illicit drug use, necessitating urgent attention for this population.

    More Related Videos

    Fentanyl Analog Screening using LC-TIMS-TOF MS/MS
    10:13

    Fentanyl Analog Screening using LC-TIMS-TOF MS/MS

    Published on: November 8, 2024

    Related Experiment Videos

    Last Updated: Jun 2, 2026

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
    10:17

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

    Published on: April 23, 2019

    Fentanyl Analog Screening using LC-TIMS-TOF MS/MS
    10:13

    Fentanyl Analog Screening using LC-TIMS-TOF MS/MS

    Published on: November 8, 2024

    Area of Science:

    • Public Health
    • Addiction Medicine
    • Pharmacology

    Background:

    • Oxycodone dependence represents a critical global public health challenge.
    • Current interventions disproportionately focus on illicit drug users.
    • A substantial population dependent on oxycodone has no history of illicit drug use.

    Discussion:

    • The oversight of non-illicit drug-using oxycodone-dependent individuals in public health strategies is a critical gap.
    • This population faces unique challenges and requires tailored interventions.
    • Failure to address this demographic exacerbates the overall oxycodone crisis.

    Key Insights:

    • The majority of oxycodone-dependent individuals may not have a history of illicit drug use.
    • Public health interventions need to broaden their scope to include non-illicit drug users.
    • Urgent attention and targeted strategies are required for this often-forgotten group.

    Outlook:

    • Future public health policies must adopt a more inclusive approach to oxycodone dependence.
    • Research is needed to understand the specific needs and pathways to dependence in non-illicit drug users.
    • Developing targeted treatment and prevention programs is essential for comprehensive crisis management.