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Published on: January 17, 2018
A supratentorial primary parenchymal paraganglioma
Sumit Thakar1, Nandita Ghosal, Sunitha P
1Department of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, EPIP Area, Whitefield, Bangalore 560066, India. sumit.thakar@gmail.com
Summary
A rare primary intracerebral paraganglioma in the brain parenchyma was surgically removed in a 40-year-old man. This case highlights an unusual intraparenchymal location for this rare benign tumor.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Neuropathology
Background:
- Primary intracerebral paragangliomas are exceptionally rare central nervous system tumors.
- The supratentorial intraparenchymal subtype is particularly uncommon, with only two prior cases documented.
- This report details a novel case to expand the understanding of these lesions.
Observation:
- A 40-year-old male presented with symptoms of increased intracranial pressure and visual decline.
- Magnetic resonance imaging (MRI) revealed a 2 cm enhancing lesion in the left frontal lobe with flow voids and significant edema.
- Magnetic resonance angiography (MRA) showed a characteristic "sun-burst" vascular pattern.
Findings:
- The intraparenchymal lesion was completely surgically excised.
- Histopathological examination confirmed the diagnosis of paraganglioma.
- Systemic evaluation excluded metastatic disease, confirming a primary intracerebral origin.
Implications:
- This case represents a unique intraparenchymal location for a primary paraganglioma.
- It underscores the importance of considering rare diagnoses in neurosurgical practice.
- Further documentation of such cases is crucial for refining diagnostic and treatment strategies for rare brain tumors.

