Related Experiment Video
Updated: Jun 2, 2026

09:31
Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
Published on: March 30, 2018
Stem cells in regenerative medicine: introduction
1Kings College London School of Medicine, Division of Women’s Health, Assisted Conception Unit, Guy’s Hospital, Great Maze Pond, London, UK.
British Medical Bulletin
|May 14, 2011
Summary
Stem cell therapy holds promise for regenerative medicine, but unverified claims mislead patients. This series aims to guide physicians with clear information on stem cell potential, safety, and efficacy.
Area of Science:
- Regenerative Medicine
- Stem Cell Science
Background:
- Extensive information exists on stem cell therapy's potential in regenerative medicine.
- Media and internet portray stem cells as a panacea, despite limited factual data.
- Patients often seek physician advice based on unsubstantiated claims.
Purpose of the Study:
- To provide physicians with guidance on stem cell therapy.
- To bridge the gap between scientific research and clinical practice.
- To offer a comprehensive overview of stem cell types and their potential.
Main Methods:
- Systematic search of the PubMed database from January 4-6, 2011.
Main Results:
- Stem cell-based therapy represents a future direction for regenerative medicine.
- Physicians struggle to evaluate complex scientific reports on cell-based therapies.
- Physicians are hesitant to advise on or endorse stem cell treatments due to lack of clear data.
Conclusions:
- A series of articles by experts will clarify the current status and future prospects of regenerative medicine.
- The series will focus on patient safety and efficacy for the healthcare industry.
- This initiative aims to empower physicians with understandable information on stem cell therapies.
Related Concept Videos
Stem Cell Therapy for Tissue Regeneration
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Embryonic Stem Cells
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Embryonic Stem Cells
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Stem Cell Culture
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...
iPS Cell Differentiation
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.

