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Imaging of polymyalgia rheumatica: indications on its pathogenesis, diagnosis and prognosis

Dario Camellino1, Marco A Cimmino

  • 1Dipartimento di Medicina Interna, Clinica Reumatologica, Università di Genova, Viale Benedetto XV, 6, 16132 Genova, Italy.

Rheumatology (Oxford, England)
|May 14, 2011
PubMed
Abstract

Insights

Imaging techniques like MRI, ultrasonography, and PET offer promising insights into polymyalgia rheumatica (PMR) pathogenesis, diagnosis, and prognosis. Further research is needed to fully explore their potential in evaluating this inflammatory disease.

Area of Science:

  • Rheumatology
  • Medical Imaging

Background:

  • Polymyalgia rheumatica (PMR) remains poorly understood regarding its causes, development, and inflammatory targets.
  • Imaging modalities offer potential for exploring PMR's underlying mechanisms and clinical aspects.

Purpose of the Study:

  • To review and appraise different imaging techniques for evaluating PMR.
  • To identify imaging clues for PMR pathogenesis, diagnosis, and prognosis.

Main Methods:

  • Systematic literature search of PubMed up to July 2010.
  • Inclusion of Cochrane Library reviews and congress abstracts (2005-2010).

Main Results:

  • 46 papers selected from 1059 retrieved.
  • Ultrasonography (US), MRI, and PET were identified as promising imaging techniques.
  • Consistent findings included bursitis and tenosynovitis; PET also showed vasculitis.

Conclusions:

  • Imaging is crucial for comprehensive PMR evaluation, aiding in understanding pathogenesis, diagnosis, and prognosis.
  • Significant potential of imaging in PMR remains unexplored, warranting further investigation.

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