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Published on: November 10, 2017
Physician adherence to the dyslipidemia guidelines is as challenging an issue as patient adherence
Geva Vashitz1, Joachim Meyer, Yisrael Parmet
1Ben-Gurion University of the Negev.
Insights
Physician non-adherence hinders guideline practice for dyslipidemia secondary prevention. Patient adherence is higher, but initiating pharmacotherapy remains challenging for physicians, especially in high-volume settings.
Area of Science:
- Cardiology
- Primary Care Medicine
- Health Services Research
Background:
- A significant gap exists between evidence-based guidelines and primary care practice for dyslipidemia secondary prevention.
- Physician and patient adherence are key factors contributing to this therapeutic gap.
Purpose of the Study:
- To differentiate physician and patient adherence to dyslipidemia secondary prevention guidelines.
- To identify factors influencing adherence in a primary care setting.
Main Methods:
- Post hoc analysis of a prospective cluster randomized trial involving 7041 patients and 127 physicians over 18 months.
- Adherence measured by physician and patient actions; correlated using multivariate logistic regressions.
Main Results:
- Physician adherence rates were low: 36.9% for lipid screening, 27.6% for pharmacotherapy up-titration, and 21.0% for initiation.
- Physician adherence correlated with frequent patient visits and higher numbers of dyslipidemic patients.
- Patient adherence was higher (83.8% for medication up-titration) but varied by guideline aspect; influenced by clinic volume, age, and physician gender.
Conclusions:
- Physician non-adherence is a primary barrier to guideline implementation in dyslipidemia secondary prevention.
- Pharmacotherapy initiation presents the greatest adherence challenge for physicians.
- High-volume settings (more patients, frequent visits) are associated with greater adherence; focus on specialized clinics and frequent follow-ups is recommended.
Background:
A wide therapeutic gap exists between evidence-based guidelines and their practice in the primary care, which is primarily attributed to physician and patient adherence.
Objective:
This study aims to differentiate physician and patient adherence to dyslipidemia secondary prevention guidelines and various factors affecting it.
Methods:
A post hoc analysis of data collected by a prospective cluster randomized trial with 7041 patients diagnosed with clinical atherosclerosis requiring secondary prevention of dyslipidemia and 127 primary care physicians over an 18-month period. Adherence was measured by physicians' and patients' actions taken according to the guidelines and correlated using multivariate logistic regressions.
Results:
Physician adherence was 36.9% for lipid profile screening, 27.6% for pharmacotherapy up-titration and 21.0% for pharmacotherapy initiation. Physician adherence was positively correlated with frequent patient visits [odds ratios (OR = 1.304)], having more dyslipidemic patients (OR = 1.304) and treating immigrants (OR = 1.268). Patient adherence was 83.8%, 71.9% and 62.6% for medication up-titration, lipid profile screening and pharmacotherapy initiation, respectively. Patient adherence was affected by attending clinics with many dyslipidemic patients (OR = 1.542), being older (OR = 1.271) and being treated by a male physician (OR = 0.870).
Conclusions:
We learn from this study that (i) physician non-adherence was a major cause for the failure to follow guidelines, (ii) pharmacotherapy initiation was the most challenging issue to tackle and (iii) greater adherence occurred mainly in high volume conditions (patients and visits). Practical implications are designated focus on metabolic condition prevention in primary care by cardiologists or primary care clinics specializing in metabolic conditions and the need to facilitate more frequent follow-up visits.
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