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The Kounis-Zavras syndrome with the Samter-Beer triad
Brian G Schwartz1, Sonak Daulat, Johannes Kuiper
1Division of Cardiology (Schwartz, Kuiper) and the Division of Allergy and Immunology (Daulat), Department of Internal Medicine, Baylor University Medical Center at Dallas.
Abstract:
We present a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma, or the Samter-Beer triad of asthma, nasal polyps, and aspirin allergy. The Kounis-Zavras syndrome, also known as Kounis syndrome, leads to angina pectoris or acute coronary syndrome secondary to coronary vasospasm in response to an allergic stimulus, leading to mast-cell degranulation of vasospastic mediators. The vasospasm can result in myocardial infarction, as it did in our patient.
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