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Updated: Jun 2, 2026

Quantitative Assessment Protocol for Facial Soft Tissue Volumetric Changes with Stereophotogrammetry
Published on: December 9, 2025
[Soft tissue profile changes by Frankel-III appliance on correcting Angle Class III malocclusion in mixed dentition]
Guo Zhao1, Sha Li, Bin-bin Chang
1Department of Stomatology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China. zhaoguo1984122@163.com
Purpose:
The purpose of this study was to evaluate the soft tissue profile changes of functional Angle Class III malocclusion in mixed dentition, and to evaluate the effectiveness of treatment with Frankel-III appliances.
Methods:
Fifteen cases of Angle Class III malocclusion in mixed dentition, 8 males and 7 females, were selected. The mean age of the patients was 9.5 years old, ranging from 7 to 12 years old. Lateral cephalometric radiograph was taken before and after the treatments and analyzed. The data was analyzed by paired t test with SPSS17.0 software package.
Results:
After the patients were treated with Frankel-III appliances in mixed dentition, Sn-Ns-Si, Ns-Sn-Pos , LiSi-Sn increased, S-Ns-Si, S-Ns-Pos,LL-EP decreased with significant difference (P<0.01). S-Ns-Sn, LsSn-Sn,Sn-Me,Ns-Me,Ul-EP increased with significant difference (P<0.05).
Conclusions:
All findings indicate that functional Angle Class III malocclusion can be corrected with Frankel-III appliances. The relationship among nose, upper lip, lower lip and chin become harmonious after treatment. The maxillary and mandibular soft tissue changes are distinct and soft tissue profile changes from Class III to Class I.

