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Updated: Jun 2, 2026
Differentiation of the SH-SY5Y Human Neuroblastoma Cell Line
Published on: February 17, 2016
Genetic stability of microsatellites in human neuroblastomas
M Gehring1, F Berthold, M Schwab
1GERMAN CANC RES CTR,DEPT CYTOGENET 0130,D-69120 HEIDELBERG,GERMANY. UNIV COLOGNE,CHILDRENS HOSP,D-50931 COLOGNE,GERMANY.
Abstract:
Genetic instability resulting from deficiency in replication error repair (RER) has been detected in a variety of human cancers. We have examined the stability of five 1p microsatellites in 51 human neuroblastomas including stages 1, 2, 3, 4 and 4s. None of the tumors showed an aberrant pattern indicating RER at any microsatellite. Our results do not support a major role for increased genetic instability as the result of deficient replication error repair in neuroblastoma.
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