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Related Experiment Videos

Movable genetic elements and antibiotic resistance in enterococci.

D B Clewell1

  • 1Department of Biological and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor 48109.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|February 1, 1990
PubMed
Summary

Enterococci use mobile genetic elements like plasmids and conjugative transposons for gene transfer. These elements spread traits such as drug resistance and hemolysin production among bacteria.

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Area of Science:

  • Microbiology
  • Bacterial Genetics
  • Horizontal Gene Transfer

Background:

  • Enterococci harbor mobile genetic elements facilitating gene transfer.
  • These elements contribute to the spread of important bacterial traits.

Purpose of the Study:

  • To review the diverse mobile genetic elements in enterococci.
  • To discuss their mechanisms of transfer and encoded functions.

Main Methods:

  • Review of existing literature on enterococcal genetic elements.
  • Analysis of plasmid and conjugative transposon systems.
  • Discussion of host range and transfer conditions.

Main Results:

  • Enterococcal plasmids show variable host ranges and transfer efficiencies (broth vs. solid surface).

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  • Conjugative transposons are widespread, self-transmissible elements in enterococci.
  • Commonly transferred traits include drug resistance, hemolysin, and bacteriocin determinants.
  • Conclusions:

    • Enterococci utilize a variety of mobile genetic elements for dissemination.
    • These elements play a significant role in bacterial adaptation and evolution.