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Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: Jun 2, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

[Psoriasis taking center stage].

C Conrad1, A-K Lapointe

  • 1Centre de psoriasis Service de dermatologie CHUV, Lausanne. curdin.conrad@chuv.ch

Revue Medicale Suisse
|May 17, 2011
PubMed
Summary
This summary is machine-generated.

Psoriasis is a chronic, T cell-mediated autoimmune disease affecting skin and joints. Its multisystem nature and relevance in studying inflammation and new treatments make it crucial across medical fields.

Related Experiment Videos

Last Updated: Jun 2, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Area of Science:

  • Immunology
  • Dermatology
  • Rheumatology

Context:

  • Psoriasis is a chronic, inflammatory, T cell-mediated autoimmune disease.
  • Primarily affects the skin and joints.
  • Recognized as a multisystem disease with numerous comorbidities.

Purpose:

  • To highlight the growing importance of psoriasis beyond dermatology and rheumatology.
  • To underscore its significance as a model for studying chronic inflammation and autoimmunity.
  • To emphasize its role in evaluating novel, pathogenesis-based treatments.

Summary:

  • Psoriasis, a T cell-mediated autoimmune condition, impacts skin and joints and is linked to various comorbidities.
  • Its systemic nature extends its relevance to multiple medical disciplines.
  • The disease serves as a key model for research into chronic inflammation, autoimmunity, and therapeutic development.

Impact:

  • Psoriasis research informs broader understanding of chronic inflammatory and autoimmune processes.
  • Its relevance as a model disease facilitates the investigation of new therapeutic strategies.
  • Increased recognition across medical fields promotes comprehensive patient care and management.