Related Experiment Video
Updated: Jun 2, 2026
02:28
Measuring Psoriasis Severity at Home
Published on: March 1, 2024
[Evaluations and measures in dermatology: new approaches]
Revue Medicale Suisse
|May 17, 2011
Summary
Digital imaging and microscopic techniques allow for regular monitoring and diagnosis of melanocytic skin lesions. These advancements enable precise measurement of skin changes in vivo, aiding clinical assessment.
Area of Science:
- Dermatology
- Medical Imaging
- Computational Pathology
Context:
- Digital imaging and advanced computing enable high-resolution photography of skin lesions.
- In vivo microscopic observation allows for detailed analysis of skin structures.
- Regular interval imaging facilitates the tracking of lesion changes over time.
Purpose:
- To present research-based techniques for monitoring and diagnosing melanocytic lesions.
- To bridge the gap between research methodologies and clinical applications.
- To highlight the utility of digital imaging and in vivo microscopy in dermatology.
Summary:
- The article details the application of digital photography and in vivo microscopy for examining skin lesions.
- These technologies facilitate the comparison of lesions at regular intervals and the measurement of subtle skin changes.
- The focus is on diagnostic and monitoring applications for melanocytic lesions.
Impact:
- Facilitates earlier and more accurate diagnosis of skin conditions like melanoma.
- Enhances the ability to monitor treatment efficacy and disease progression.
- Integrates cutting-edge research tools into routine dermatological practice.
Related Concept Videos
01:14Changes in Skin Color: Clinical Perspectives
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
01:16Confocal Fluorescence Microscopy
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
01:20Measurement of Bioavailability: Pharmacodynamic Methods
Pharmacodynamic methods provide insights into a drug's effects on physiological processes over time and play a crucial role in understanding bioavailability and therapeutic efficacy. These methods can be broadly classified into acute pharmacological and therapeutic response approaches, each with distinct mechanisms and applications.The acute pharmacological response method directly correlates a drug's physiological effects, such as ECG or pupil diameter changes, to its time course in the body.
01:23Drug Concentrations: Measurements
Drug concentration is the quantity of a drug present in a biological sample. Measuring drug amounts in biological samples allows the clinician to understand how a drug is absorbed, distributed, metabolized, and excreted. Samples can be obtained through invasive or non-invasive methods. Invasive techniques involve surgical or parenteral interventions to gather blood, cerebrospinal fluid, or tissue biopsy. Conversely, non-invasive approaches provide samples like urine, feces, and saliva.
Plasma —...
Plasma —...
01:27Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...