Related Experiment Video
Updated: Jun 2, 2026

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
Published on: June 5, 2019
The 220-age equation does not predict maximum heart rate in children and adolescents
Olaf Verschuren1, Désirée B Maltais1, Tim Takken1
1Centre of Excellence, Rehabilitation Centre 'De Hoogstraat', Utrecht, the Netherlands. Partner of NetChild, Network for Childhood Disability Research, Utrecht, the Netherlands. University Medical Center, Rudolf Magnus Institute of Neuroscience Department of Rehabilitation, Nursing Science and Sports, Utrecht, the Netherlands. Department of Rehabilitation, Laval University, Quebec City, Quebec, Canada. Centre for Interdisciplinary Research in Rehabilitation and Social Integration, Quebec City, Quebec, Canada. School of Clinical Health Sciences, Department of Physical Therapy Science, Utrecht University, Utrecht, the Netherlands. Child Development & Exercise Center, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht, the Netherlands.
Abstract:
Our primary purpose was to provide maximum heart rate (HR(max) ) values for ambulatory children with cerebral palsy (CP). The secondary purpose was to determine the effects of age, sex, ambulatory ability, height, and weight on HR(max) . In 362 ambulatory children and adolescents with CP (213 males and 149 females; age range 6-19y; 195 spastic unilateral, 162 spastic bilateral, and five ataxic CP), HR(max) was measured during a 10-m (Gross Motor Function Classification System [GMFCS] levels I and II) or 7.5 m (GMFCS level III) shuttle run test. The mean HR(max) was 194 (SD 9.9) beats per minute (bpm), with a 95% prediction interval between 174 and 214 bpm. No associations were found in HR(max) related to age, sex, ambulatory ability, height, and weight. Since the HR(max) did not vary with age, equations such as 220-age are not appropriate. When direct evaluation of HR(max) with exercise testing is not feasible, we suggest the mean value of 194 bpm be considered as an estimate of HR(max) at the individual level.
Related Concept Videos
Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Regulation of Heart Rates
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...

