Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Signal transduction in bacteria.

J B Stock1, A M Stock, J M Mottonen

  • 1Department of Molecular Biology, Princeton University, New Jersey 08544.

Nature
|March 29, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anti-inflammatory and anti-bacterial properties of tetramethylhexadecenyl succinyl cysteine (TSC): a skin-protecting cosmetic functional ingredient.

International journal of cosmetic science·2014
Same author

Synthesis and biochemical characterization of a phosphorylated analogue of the response regulator CheB.

Biochemistry·2001
Same author

Histidine kinases and response regulator proteins in two-component signaling systems.

Trends in biochemical sciences·2001
Same author

Crystal structure of the CheA histidine phosphotransfer domain that mediates response regulator phosphorylation in bacterial chemotaxis.

The Journal of biological chemistry·2001
Same author

Phosphorylation causes subtle changes in solvent accessibility at the interdomain interface of methylesterase CheB.

Journal of molecular biology·2001
Same author

Response-regulator phosphorylation and activation: a two-way street?

Trends in microbiology·2001
Same journal

Daily briefing: 'Cyborg' cockroaches breathe underwater with printed suit.

Nature·2026
Same journal

China boosts prestigious grants for young scientists - will it ease competition?

Nature·2026
Same journal

Incoming US science academy chief vows to 'double down' on research.

Nature·2026
Same journal

Author Correction: Synthesis of enantioenriched atropisomers by biocatalytic deracemization.

Nature·2026
Same journal

Electrodeposited self-assembled molecules for perovskite photovoltaics.

Nature·2026
Same journal

Neutrino's nursery found: the 'Shadow Blaster'.

Nature·2026
See all related articles

Microbial cells sense environmental changes using a phosphotransfer network. This system regulates cell motility and gene expression through regulatory proteins and signal transduction.

Area of Science:

  • Microbiology
  • Cellular Biology
  • Biochemistry

Background:

  • Cells possess sophisticated mechanisms to detect and respond to environmental stimuli.
  • Simple microbial systems utilize intricate signaling pathways to process external information.

Purpose of the Study:

  • To elucidate the role of phosphotransfer networks in microbial environmental responses.
  • To understand how signal transduction pathways regulate cellular functions like motility and gene expression.

Main Methods:

  • Investigated sensory receptor pathways in microbial systems.
  • Analyzed the phosphotransfer network involving histidine and aspartate phosphorylation.
  • Examined the coupling of environmental signals to response elements.

Related Experiment Videos

Main Results:

  • Identified a regulatory protein circuitry for signal transduction.
  • Demonstrated high-energy phosphoryl group transfer from histidine to aspartate.
  • Showcased the network's role in controlling cell motility and gene expression.

Conclusions:

  • The phosphotransfer network is crucial for microbial adaptation to environmental fluctuations.
  • Signal transduction via phosphotransfer networks provides a mechanism for integrating environmental cues and cellular responses.