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Related Concept Videos

Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
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Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
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The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
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Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Published on: May 16, 2025

[Seborrheic dermatitis in clinical practice].

Francesca Rovelli, Santo Raffaele Mercuri, Luigi Naldi

    Recenti Progressi in Medicina
    |May 17, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Seborrheic dermatitis is a common, relapsing inflammatory skin condition. Topical antifungal treatments, like ketoconazole, are effective for managing symptoms and maintaining remission.

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    Area of Science:

    • Dermatology
    • Mycology
    • Inflammation

    Background:

    • Seborrheic dermatitis is a frequent, chronic inflammatory skin disorder.
    • It presents as scaling and erythematous patches, primarily affecting sebaceous gland-rich areas.
    • The ubiquitous, lipid-dependent fungi of the genus Malassezia are implicated in its pathogenesis.

    Discussion:

    • Topical antifungal agents, such as ketoconazole, are the primary treatment modality.
    • Intermittent application of antifungals can effectively maintain remission.
    • The formulation vehicle of topical treatments may also influence treatment efficacy.

    Key Insights:

    • Malassezia fungi play a key role in seborrheic dermatitis.
    • Topical antifungals are the mainstay of treatment for this condition.
    • Vehicle properties can impact treatment outcomes.

    Outlook:

    • Further research is needed to refine diagnostic criteria for seborrheic dermatitis.
    • Development of improved severity measures and outcome variables is essential.
    • Enhanced clinical trial design and evidence-based clinical practice require better outcome measures.