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Published on: January 1, 2016
Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and
Erlanio O Sousa1, Thiago S Almeida, Fabíola F G Rodrigues
1Vice-Reitoria de Pesquisa e Pós-Gradução, Universidade de Fortaleza, Av. Washington Soares 1321, Edson Queiroz, 60811-905, Fortaleza-CE, Brasil.
Objective:
In this work, we report the antibacterial and modulatory activity of Lantana montevidensis Briq.
Materials And Methods:
The antibacterial activities of leaf (LELm) and root (RELm) extracts alone or in association with aminoglycosides were determined by a microdilution test. Multiresistant strains of Escherichia coli (Ec 27) and Staphylococcus aureus (Sa 358) were used.
Results:
The results show the inhibitory activity of LELm against E. coli (minimal inhibitory concentration [MIC] 16 μg/mL) and S. aureus (MIC 128 μg/mL). The synergistic effect of the extracts and aminoglycosides was verified too. The maximum effects were obtained with RELm with gentamicin against E. coli with MIC reduction (312 to 2 μL).
Conclusion:
The data from this study are indicative of the activity antibacterial of extracts of L. montevidensis and its potential in modifying the resistance of aminoglycosides.
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