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Updated: Jun 2, 2026
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A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
Published on: July 5, 2017
A clinicopathologic study of excised conjunctival lesions
Laila Hassan Mohamad Elshazly1
1Department of Ocular and Pathology, Memorial Institute of Ophthalmology, Cairo, Egypt.
Middle East African Journal of Ophthalmology
|May 17, 2011
Summary
This study found benign conjunctival lesions, like pyogenic granulomas, are most common. Precancerous ocular surface squamous neoplasia (OSSN) was noted, potentially linked to sun exposure.
Area of Science:
- Ophthalmology
- Pathology
- Oncology
Background:
- Conjunctival lesions encompass a wide range of conditions affecting the eye's surface.
- Understanding the frequency of different conjunctival lesions is crucial for diagnosis and treatment planning.
Purpose of the Study:
- To determine the frequency of various excised conjunctival lesions over a decade.
- To analyze the prevalence of benign, precancerous, and malignant conjunctival lesions.
Main Methods:
- Retrospective analysis of 192 conjunctival specimens with tissue diagnoses from 1998 to 2008.
- Data collected from a pathology department's records.
Main Results:
- Pyogenic granulomas were the most frequent lesion (30.7%), followed by pigmented epithelial tumors (22.9%).
- Ocular surface squamous neoplasia (OSSN), a precancerous lesion, was found in 10.9% of cases, predominantly in older individuals.
- Malignant lesions were less common than reported in other studies.
Conclusions:
- Benign lesions constitute the majority of histologically diagnosed conjunctival lesions.
- The incidence of malignant conjunctival lesions appears lower than previously reported.
- A significant proportion of precancerous OSSN cases may be linked to environmental factors like sun exposure.
