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Related Experiment Video

Updated: Jun 2, 2026

Murine Bilateral Renal Lymphadenectomy

Murine Bilateral Renal Lymphadenectomy

Published on: December 30, 2025

Lupus, the current therapeutic approaches.

M Wong¹, A La Cava

¹Division of Rheumatology at the David Geffen School of Medicine, University of California Los Angeles, California, USA. maidawong@mednet.ucla.edu

Drugs of Today (Barcelona, Spain : 1998)

|May 17, 2011

Summary

This summary is machine-generated.

Systemic lupus erythematosus (SLE) management is complex. This review covers current SLE therapies and emerging treatments like biologics and cell-based options, offering new hope for patients.

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The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice

Published on: November 1, 2015

Area of Science:

Immunology
Rheumatology
Pharmacology

Background:

Systemic lupus erythematosus (SLE) presents diverse clinical features, complicating management.
Current immunosuppressive therapies for SLE carry substantial side effects.
Recent advances in understanding SLE pathogenesis enable targeted therapeutic strategies.

Purpose of the Study:

To review current induction and maintenance therapies for SLE.
To discuss novel and emerging therapeutic modalities for SLE management.

Main Methods:

Review of existing literature on SLE management.
Analysis of current and investigational therapeutic agents.
Discussion of biologics, peptides, oligonucleotides, and cell-based therapies.

Main Results:

Standard SLE treatments involve immunosuppressants with known side effects.
Targeted therapies are being developed based on SLE pathogenesis.
Emerging treatments include monoclonal antibodies, peptides, oligonucleotides, and cell therapies.

Conclusions:

New therapeutic avenues for SLE are emerging, targeting specific molecular and cellular pathways.
Biologics and other advanced therapies show promise for improved SLE management.
Further research and clinical trials are essential for optimizing SLE treatment strategies.