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Updated: Jun 2, 2026

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
Published on: March 9, 2017
A novel and unusually long-lived chemiluminophore based on the 7-hydroxycoumarin scaffold
Jan Kočí1, Virgile Grandclaude, Marc Massonneau
1Equipe de Chimie Bio-Organique, COBRA-CNRS UMR 6014 & FR 3038, rue Lucien Tesnière, 76131 Mont-Saint-Aignan, France.
Abstract:
Synthesis and chemiluminescent properties of a new 1,2-dioxetane chemiluminophore bearing a 7-hydroxycoumarin moiety are presented. The 1,2-dioxetane decomposition ended up with strong and long-lived emission of light. This new structure opens way to the development of a new generation of bright chemiluminescent bio-probes.
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