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Updated: Jun 2, 2026

Modified Radical Neck Dissection for Cervical Metastasis
Published on: February 20, 2026
General-hospital experience in treating neck nodes from unknown primaries
A Bono1, S Zurrida, C Cacioppo
1IST NAZL TUMORI,DIV SURG ONCOL B,VIA G VENEZIAN 1,I-20133 MILAN,ITALY. IST NAZL TUMORI,DIV DIAGNOST ONCOL,I-20133 MILAN,ITALY. IST NAZL TUMORI,OUTPATIENT CLIN,I-20133 MILAN,ITALY. OSPED NIGUARDA CA GRANDA,FALCK DIV MED ONCOL,MILAN,ITALY. IST NAZL TUMORI,DIV HEAD & NECK SURG ONCOL,I-20133 MILAN,ITALY.
Abstract:
Forty cases of cervical (excluding supraclavicular) node metastases from unknown primary tumors were observed at the medical oncology department of a large general hospital. Histologically they were epidermoid carcinoma (18 cases), undifferentiated carcinoma (16 cases) and adenocarcinoma (6 cases). In 8 patients the primary was subsequently diagnosed. Four patients were untreatable or refused treatment when diagnosed. The 3-year survival of the 36 treated patients was only 22% - indicating a poor prognosis is for this uncommon form of presentation. Patients should be treated as aggressively as possible in an attempt to eradicate the occult primary.
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