Related Experiment Video
Updated: Jun 2, 2026

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells
Published on: June 13, 2018
Primary pleomorphic liposarcoma of bone in an adolescent: imaging features of a rare entity
Darshana D Rasalkar1, Louis T C Chow, Winnie Chiu-wing Chu
1Department of Imaging and Interventional Radiology, Prince of Wales Hospital, Ngan Shing St, Shatin, New Territories, Hong Kong.
Abstract:
We report a rare case of a primary osseous pleomorphic liposarcoma of the distal femur in a 13-year-old boy. Primary liposarcoma of bone is a very rare malignant tumour originating from primitive mesenchymal cells rather than mature adipose tissue. Pleomorphic liposarcoma is the least common of the eight known histological subtypes in the WHO classification. The entity is not previously reported in children. This is the third reported case of pleomorphic liposarcoma of the bone, and the first reported case presenting in adolescence. We describe the computed tomography and magnetic resonance imaging features of this rare bony tumour.

