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Published on: April 19, 2024
[Cycloferon efficacy in viral and bacterial diseases of children (clinical review)]
Insights
Cycloferon, an interferon inducer, demonstrates significant efficacy in treating various childhood illnesses, including infections and asthma. It also prevents post-vaccination complications and corrects gut dysbiosis in children.
Area of Science:
- Immunology
- Pediatrics
- Pharmacology
Background:
- Cycloferon is an interferon inducer with immunomodulatory properties.
- Its therapeutic efficacy has been documented in various clinical settings.
Purpose of the Study:
- To review the pharmacotherapeutic efficacy of Cycloferon in pediatric patients.
- To evaluate its use in treating socially significant childhood diseases and post-vaccination complications.
Main Methods:
- Literature data review and analysis of clinical findings.
- Assessment of Cycloferon's effects in various pediatric conditions, including infections, asthma, allergies, and surgical pathologies.
- Evaluation of its impact on autoimmune processes and gut microflora.
Main Results:
- Cycloferon effectively treats viral respiratory infections, bronchial asthma, and allergic conditions with immune disturbances.
- It inhibits autoimmune processes, preventing post-vaccination complications in frequently ill children.
- The drug is effective in treating gastrointestinal and intestinal infections (viral and bacterial), correcting intestinal dysbiosis in 95% of cases.
- It reduces postoperative complications in appendicular peritonitis and corrects immune disturbances in chronic viral hepatitis B and C.
Conclusions:
- Cycloferon is a safe and effective drug for a wide range of pediatric conditions.
- Its immunomodulatory and antiviral properties make it valuable in treating infections, allergies, and in post-vaccination care.
- Recommended for correcting intestinal dysbiosis and as part of complex therapy for surgical and chronic viral infections in children.
Abstract:
The authors' findings and literature data on the pharmacotherapeut efficacy of cycloferon, an interferon inductor (immunomodulators) are described. The drug effect in the treatment of various socially significant children' diseases, including acute respiratory tract viral infection, bronchial asthma, allergic conditions with infection protection disturbances, mycoplasmic infection, bronchopulmonary complications of acute respiratory tract viral infection with low intensity of free radical oxidation is indicated. The use of cycloferon at the background of vaccination was shown to provide inhibition of the autoimmune processes causing postvaccinal complications in frequently ill children. The results of the use of cycloferon in the treatment of gastrointestinal tract and intestinal infections of both the viral and bacterial genesis are discussed. Cycferon is recommended to be used for correction of the intestine dysbiosis (the microflora level came to normal in 95% of the children). The use of the drug in surgical pathology and in particular in appendicular peritonitis for decreasing the postoperative complications and correction of the immune disturbances due to chronic viral hepatitis C and B in children under the complex therapy is described. The cycloferon safety and efficacy were confirmed by the postmarketing randomized trials.
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