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The spin trapping of superoxide with M4PO (3,3,5,5-tetramethylpyrroline-N-oxide)
1ESR Center, University of Iowa, Iowa City 52242.
Free Radical Biology & Medicine
|January 1, 1990
Abstract:
The spin trap 3,3,5,5-tetramethylpyrroline-N-oxide (M4PO) reacts with superoxide to produce a short-lived spin adduct (M4PO/.OOH, AN = 14.0 G, AH = 6.5 G) that decays by a first-order process (t1/2 approximately 35 s at pH 7.4). This short lifetime may limit its usefulness in studies of superoxide.