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Updated: Jun 1, 2026
09:37
Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Cutaneous manifestations of malignancy
1Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA. tswright@texaschildrens.org
Current Opinion in Pediatrics
|May 18, 2011
Summary
Pediatric cancers like leukemia, lymphoma, and neuroblastoma can manifest as skin lesions. Recognizing these cutaneous findings is crucial for early diagnosis and improved patient outcomes in childhood malignancies.
Area of Science:
- Pediatric oncology
- Dermatology
- Medical education
Background:
- Cutaneous manifestations can be primary or secondary to underlying pediatric malignancies.
- Skin lesions may precede, coincide with, or follow a cancer diagnosis.
Purpose of the Study:
- To educate medical providers on pediatric malignancies presenting with cutaneous findings.
- To highlight skin manifestations of leukemias, lymphomas, neuroblastoma, sarcomas, and Langerhans cell histiocytosis.
Main Methods:
- Literature review focusing on cutaneous features of pediatric cancers.
- Summary of typical and unusual case reports of malignancies with skin lesions.
Main Results:
- A diverse spectrum of skin lesions is associated with childhood systemic malignancies.
- Includes common presentations and rare, atypical cutaneous findings.
Conclusions:
- Cutaneous signs are important indicators of underlying pediatric malignancy.
- Clinician awareness of these dermatologic features is vital for timely diagnosis and prognosis.
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