Related Experiment Video
Updated: Jun 1, 2026
![Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F2755.jpg&w=3840&q=50)
Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)
Published on: June 28, 2011
5-Fluoro-2-(4-iodo-phen-yl)-3-methyl-sulfinyl-1-benzofuran
Abstract:
In the title compound, C(15)H(10)FIO(2)S, the O atom and the methyl group of the methyl-sulfinyl substituent lie on opposite sides of the plane through the benzofuran fragment. The 4-iodo-phenyl ring is rotated out of the benzofuran plane by a dihedral angle of 39.4 (1)°. The crystal structure is stabilized by an inter-molecular C-H⋯O hydrogen bond and an I⋯O halogen bond [3.055 (2) Å]. The crystal structure also exhibits an inter-molecular C-H⋯π inter-action between the methyl H atom and the 4-iodo-phenyl ring of an adjacent benzofuran mol-ecule, and aromatic π-π inter-actions between the benzene rings of neighbouring benzofuran systems [centroid-centroid distance = 3.558 (3) Å].
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