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Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
3-(4-Chloro-phen-yl)-1-(4-nitro-phen-yl)benzo[f]quinoline
Shu-Liang Wang1, Qing Li, Xiang-Shan Wang
1School of Chemistry and Chemical Engineering, Xuzhou Normal University, Xuzhou Jiangsu 221116, People's Republic of China.
Abstract:
In the title compound, C(25)H(15)ClN(2)O(2), the pyridine ring is inclined at angles of 6.89 (7), 4.24 (9) and 66.98 (4)° with respect to the naphthalene, chloro-phenyl and nitro-phenyl rings, respectively. The two substituent aromatic rings make a dihedral angle of 71.1 (1)° with one another. C-H⋯π and π-π stacking are present in the crystal structure; the π-π stacking [centroid-centroid distance between the pyridyl rings of adjacent mol-ecules= 3.7838 (11) Å] links the mol-ecules into dimers, while the C-H⋯Cg type π-ring inter-actons link the mol-ecules into a chain structure along c.
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