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Updated: Jun 1, 2026
08:43
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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2-(4-Methyl-anilino)acetohydrazide.
Summary
This study details the crystal structure of a molecule C(9)H(13)N(3)O, revealing a planar hydrazide group. The structure forms a 2D network via hydrogen bonds and weak interactions.
Area of Science:
- Crystallography
- Molecular Structure
- Supramolecular Chemistry
Background:
- Understanding molecular interactions is crucial for materials science.
- Crystal engineering relies on predicting and controlling intermolecular forces.
Purpose of the Study:
- To elucidate the crystal structure and intermolecular interactions of C(9)H(13)N(3)O.
- To analyze the geometric parameters and hydrogen bonding network.
Main Methods:
- Single-crystal X-ray diffraction analysis.
- Analysis of bond lengths, bond angles, and dihedral angles.
- Identification of hydrogen bonds (N-H⋯O, N-H⋯N) and C-H⋯N interactions.
Main Results:
- The hydrazide group in C(9)H(13)N(3)O exhibits near planarity (max deviation 0.028 Å).
- A dihedral angle of 83.34° exists between the hydrazide plane and the benzene ring.
- A 2D supramolecular network is formed via intermolecular hydrogen bonds and weak C-H⋯π interactions.
Conclusions:
- The molecule C(9)H(13)N(3)O displays specific planarity and orientation of its functional groups.
- Intermolecular hydrogen bonds and weak interactions dictate the formation of a stable 2D network in the crystal lattice.
- This structural information contributes to the understanding of molecular assembly and crystal design.
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