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Updated: Jun 1, 2026
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Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
(RS)-3-Acetyl-2-methyl-4-(3-nitro-phen-yl)-1,4,5,6,7,8-hexa-hydro-quinolin-5-one
Dong'e Wang1, Yu-Zhou Wang, Muhtar Turhong
1Department of Chemistry, Kashgar Teachers' College, Kashgar 844000, People's Republic of China.
Abstract:
In the title compound, C(18)H(18)N(2)O(4), the nitro group, a methyl group, the acetyl group and some atoms of the dihydro-quinolinone group are disordered over two sites with the ratio of occupancies fixed at 0.57:0.43. The relationship between the major and minor components of disorder is that of diastereomers. In the crystal structure, inter-molecular N-H⋯O, weak C-H⋯O and C-H⋯π inter-actions link the mol-ecules into two-dimensional layers running parallel to the (010) plane.
