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Updated: Jun 1, 2026
11:01
Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(E)-N'-(2,5-Dimethoxy-benzyl-idene)-3,4-dihydroxy-benzohydrazide monohydrate
Summary
This study details the crystal structure of a compound, C(16)H(16)N(2)O(5)·H(2)O. It reveals a specific dihedral angle between benzene rings and describes intra-molecular and inter-molecular hydrogen bonding in its three-dimensional network.
Area of Science:
- Crystallography
- Chemical Physics
- Materials Science
Background:
- Understanding molecular interactions is crucial for materials design.
- Hydrogen bonding plays a significant role in crystal packing and material properties.
Purpose of the Study:
- To elucidate the crystal structure of the compound C(16)H(16)N(2)O(5)·H(2)O.
- To analyze the dihedral angle between benzene rings and hydrogen bonding patterns.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond lengths, bond angles, and hydrogen bond geometry.
Main Results:
- The dihedral angle between the two benzene rings was determined to be 25.9(1)°.
- Intra-molecular hydrogen bonds (O-H⋯O and N-H⋯O) were identified.
- A three-dimensional network was formed through inter-molecular O-H⋯O and O-H⋯(O,O) hydrogen bonds.
Conclusions:
- The crystal structure of C(16)H(16)N(2)O(5)·H(2)O is characterized by a specific dihedral angle and extensive hydrogen bonding.
- The observed hydrogen bonding network dictates the three-dimensional arrangement of molecules in the crystal.
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