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Updated: Jun 1, 2026
05:59
Green Synthesis of Quinoline-Based Ionic Liquid
Published on: September 27, 2024
2-Chloro-6-methyl-quinoline-3-carbaldehyde
Summary
The crystal structure of a novel quinoline derivative (C11H8ClNO) reveals an almost planar fused-ring system. The attached formyl group exhibits a slight deviation from this plane.
Area of Science:
- Organic Chemistry
- Crystallography
- Molecular Structure
Background:
- Quinoline derivatives are important scaffolds in medicinal chemistry.
- Understanding the precise three-dimensional structure of novel compounds is crucial for predicting their properties and interactions.
Purpose of the Study:
- To determine the solid-state structure of the title compound, C11H8ClNO.
- To analyze the planarity of the quinolinyl fused-ring system and the orientation of the formyl group.
Main Methods:
- Single-crystal X-ray diffraction analysis was employed.
- The molecular geometry, including bond lengths, angles, and torsion angles, was determined.
Main Results:
- The quinolinyl fused-ring system of C11H8ClNO was found to be nearly planar, with a root-mean-square deviation of 0.013 Å.
- The formyl group displayed a slight deviation from the fused ring plane, indicated by a C-C-C-O torsion angle of 13.5(4)°.
Conclusions:
- The structural analysis provides fundamental data on the molecular conformation of this quinoline derivative.
- The observed planarity and slight torsion angle offer insights into potential intermolecular interactions and reactivity.
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